Hi - lots of news swirling about the new type 1 research in the New England Journal of Medicine yesterday. As we wrote about in our Revolution Health blog (https://www.revolutionhealth.com/blogs/kellyclose/exciting-if-early-st-3594), Dr. Jay Skyler of the University of Miami, one of the country's leading thinkers about prevention of diabetes - and author of the editorial going alongside the research - emphasized in a note to us this morning that there are positives and negatives both - our interpretation was that it's too early to get wildly excited but it's definitely time to watch what's happening in this research. First, he says the work is promising due to the results that the group showed - most went off insulin for some period, and one has been off insulin for three years, without any major adverse events (yet). Dr. Skyler stressed, too, that there are unknowns - the trial had no control group, it was only 14 subjects, and the follow-up too short. As Scott Strumello points out in his comment, this also didn't work on the first subject - and clearly this research is all about newly diagnosed. More research is needed, says Dr. Skyler - now, hopefully, it can be funded in the US. Of interest is that J&J funded the study. We'll see what else we can learn on this at the AACE, now going on in Seattle.